Doxorubicin free base

• CAT Number: I006525
• CAS Number: 23214-92-8 (free base)
• Molecular Formula: C27H29NO11
• Molecular Weight: 543.52
• Purity: 97%
• Synonyms: ADR; chloridrato de doxorrubicina. Adriamycin; Adriacin; Adriblastina; Adriblastine; Adrimedac; DOXOCELL; Doxolem; Doxorubin; Farmiblastina; Rubex. Abbreviations: ADM; Adria; DOX. Code name: FI106;;(8S,10S)-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-meth
• Target: Antibody-drug Conjugate/ADC Related
• Solubility: This product has low solubility in all common solvents.
• Storage: 0 - 4°C for short term or -20 °C for long term
• Related CAS: 56420-45-2 25316-40-9 56390-09-1 57918-24-8
• IUPAC Name: (7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
• InChI: InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1
• InChIKey: AOJJSUZBOXZQNB-TZSSRYMLSA-N
• SMILES: C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)O

Doxorubicin Free Base（Cat No.:I006525）is a powerful anthracycline antibiotic used as a chemotherapy agent. It works by intercalating into DNA, inhibiting topoisomerase II, and generating free radicals, which cause DNA strand breaks and prevent cell replication. Doxorubicin is widely used in the treatment of various cancers, including breast cancer, lymphoma, and leukemia. Its effectiveness in disrupting DNA synthesis makes it a cornerstone of cancer therapy. However, it is associated with cardiotoxicity, requiring careful monitoring during treatment. Its free base form allows flexibility in drug formulation and research applications.