For research use only. Not for therapeutic Use.
Doxycycline Monohydrate(Cat No.:M085028)is a broad-spectrum tetracycline antibiotic widely used to treat various bacterial infections. It inhibits protein synthesis by binding to the 30S ribosomal subunit, making it effective against gram-positive and gram-negative bacteria. Doxycycline monohydrate is commonly used to treat respiratory infections, acne, urinary tract infections, and sexually transmitted diseases. Its extended half-life allows for less frequent dosing compared to other tetracyclines. Additionally, doxycycline has anti-inflammatory properties, making it a useful option in conditions like rosacea and certain inflammatory diseases.
Catalog Number | M085028 |
CAS Number | 17086-28-1 |
Molecular Formula | C22H24N2O8 H |
Purity | ≥95% |
Target | Anti-infection |
Storage | -80°C |
IUPAC Name | (4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrate |
InChI | InChI=1S/C22H24N2O8.H2O/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-7,10,14-15,17,25-27,30,32H,1-3H3,(H2,23,31);1H2/t7-,10+,14+,15-,17-,22-;/m0./s1 |
InChIKey | FZKWRPSUNUOXKJ-CVHRZJFOSA-N |
SMILES | C[C@@H]1[C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O |
Reference | Hydrogenolysis studies in the tetracycline series – 6-Deoxytetracyclines. Stephens C.R. et al. J. Am. Chem. Soc. 1958, 80, 5324.<br/><br/>Comparison of in vitro activity and clinical pharmacology of doxycycline with other tetracyclines. Rosenblatt J.E. et al. Antimicrob. Agents Chemother. 1966, 6, 134.</span></p> |