For research use only. Not for therapeutic Use.
DP-1, a degradation product of SDC-TRAP-0063, is a fragment of Ganetespib. Ganetespib is a heat shock protein 90 (HSP90) inhibitor with anti-tumor activity[1].
DP-1 is the SDC-TRAP-0063 degradation product which can be found in plasma, tumor and heart[1].
| Catalog Number | I045317 |
| CAS Number | 1472616-61-7 |
| Synonyms | 3-(2,4-dihydroxy-5-propan-2-ylphenyl)-4-[1-(2-piperidin-4-ylethyl)indol-5-yl]-1H-1,2,4-triazol-5-one |
| Molecular Formula | C26H31N5O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C26H31N5O3/c1-16(2)20-14-21(24(33)15-23(20)32)25-28-29-26(34)31(25)19-3-4-22-18(13-19)8-12-30(22)11-7-17-5-9-27-10-6-17/h3-4,8,12-17,27,32-33H,5-7,9-11H2,1-2H3,(H,29,34) |
| InChIKey | CPMBELNSUCVCNT-UHFFFAOYSA-N |
| SMILES | CC(C)C1=C(C=C(C(=C1)C2=NNC(=O)N2C3=CC4=C(C=C3)N(C=C4)CCC5CCNCC5)O)O |
| Reference | [1]. Chimmanamada DU, et, al. Targeted therapeutics. US20140079636A1. |
