For research use only. Not for therapeutic Use.
DpC is an anti-tumor agent. DpC inhibits cancer cell proliferation (IC50: 0.007-0.096 渭M). DpC synergizes with multiple anti-cancer therapeutics[1].
| Catalog Number | I040959 |
| CAS Number | 1382469-39-7 |
| Synonyms | 1-cyclohexyl-3-(dipyridin-2-ylmethylideneamino)-1-methylthiourea |
| Molecular Formula | C19H23N5S |
| Purity | ≥95% |
| InChI | InChI=1S/C19H23N5S/c1-24(15-9-3-2-4-10-15)19(25)23-22-18(16-11-5-7-13-20-16)17-12-6-8-14-21-17/h5-8,11-15H,2-4,9-10H2,1H3,(H,23,25) |
| InChIKey | GNLZNQJBZNOUBM-UHFFFAOYSA-N |
| SMILES | CN(C1CCCCC1)C(=S)NN=C(C2=CC=CC=N2)C3=CC=CC=N3 |
| Reference | [1]. Dharmasivam M, et al. The thiosemicarbazone, DpC, broadly synergizes with multiple anti-cancer therapeutics and demonstrates temperature- and energy-dependent uptake by tumor cells. Biochim Biophys Acta Gen Subj. 2022 Aug;1866(8):130152. |
