For research use only. Not for therapeutic Use.
DpC (Di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone)(CAT: I040959) is a potent anti-tumor agent that inhibits cancer cell proliferation with an IC₅₀ range of 0.007–0.096 μM. As a second-generation thiosemicarbazone, it disrupts metal ion homeostasis, inducing oxidative stress and apoptosis in cancer cells. DpC has demonstrated synergistic effects with multiple anti-cancer therapeutics, enhancing treatment efficacy. It is under investigation for its broad-spectrum anticancer potential, including neuroblastoma and drug-resistant tumors. Suitable for biochemical, cellular, and preclinical studies, DpC is a promising tool for cancer research and drug discovery. For research use only; not for human or clinical applications.
| CAS Number | 1382469-39-7 |
| Synonyms | 1-cyclohexyl-3-(dipyridin-2-ylmethylideneamino)-1-methylthiourea |
| Molecular Formula | C19H23N5S |
| Purity | ≥95% |
| IUPAC Name | 1-cyclohexyl-3-(dipyridin-2-ylmethylideneamino)-1-methylthiourea |
| InChI | InChI=1S/C19H23N5S/c1-24(15-9-3-2-4-10-15)19(25)23-22-18(16-11-5-7-13-20-16)17-12-6-8-14-21-17/h5-8,11-15H,2-4,9-10H2,1H3,(H,23,25) |
| InChIKey | GNLZNQJBZNOUBM-UHFFFAOYSA-N |
| SMILES | CN(C1CCCCC1)C(=S)NN=C(C2=CC=CC=N2)C3=CC=CC=N3 |
