DPP-IV-IN-2

• CAT Number: I013007
• CAS Number: 136259-18-2
• Molecular Formula: C18H26N4O5
• Molecular Weight: 378.42
• Purity: ≥95%
• Synonyms: (4-nitrophenyl)methyl N-[(5S)-5-amino-6-oxo-6-pyrrolidin-1-ylhexyl]carbamate
• InChI: InChI=1S/C18H26N4O5/c19-16(17(23)21-11-3-4-12-21)5-1-2-10-20-18(24)27-13-14-6-8-15(9-7-14)22(25)26/h6-9,16H,1-5,10-13,19H2,(H,20,24)/t16-/m0/s1
• InChIKey: YDYSCRZHYWLSPQ-INIZCTEOSA-N
• SMILES: C1CCN(C1)C(=O)C(CCCCNC(=O)OCC2=CC=C(C=C2)[N+](=O)[O-])N

DPP-IV-IN-2 is an inhibitor of both dipeptidyl peptidase IV (DPIV) and DP8/9 with IC50s of 0.1 and 0.95 μM, respectively.

Reference

[1]. Ansorge S, et al. Novel aspects of cellular action of dipeptidyl peptidase IV/CD26. Biol Chem. 2011 Mar;392(3):153-68.
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