DPPG-Na

• CAT Number: I026507
• CAS Number: 67232-81-9
• Molecular Formula: C38H73Na2O10P
• Molecular Weight: 766.95
• Purity: 96%
• Synonyms: DPPG-Na; 1,2-Dihexadecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) sodium salt, L-α-Phosphatidyl-DL-glycerol, dipalmitoyl, DPPG-Na, Hexadecanoic acid 1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester, PG(16:0/16:0)
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 1,2-Dipalmitoyl-sn-glycero-3-phospho-rac-glycerol sodium salt
• InChI: InChI=1S/C38H75O10P.2Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-36(41)46-32-34(33-47-38(35(40)31-39)49(43,44)45)48-37(42)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;;/h34-35,38-40H,3-33H2,1-2H3,(H2,43,44,45);;/q;2*+1/p-2/t34-,35?,38?;;/m1../s1
• InChIKey: SGMIUGBRFZAMMZ-VMXXRITKSA-L
• SMILES: CCCCCCCCCCCCCCCC(O[C@@H](COC(P([O-])([O-])=O)C(CO)O)COC(CCCCCCCCCCCCCCC)=O)=O.[Na+].[Na+]

DPPG-Na (CAT: I026507) refers to dipalmitoyl phosphatidylglycerol sodium salt. It is a phospholipid derivative commonly used in research and pharmaceutical applications. DPPG-Na plays a role in stabilizing lipid bilayers and modulating membrane properties. It is often utilized in studies related to liposome formulations, drug delivery systems, and membrane interactions. The sodium salt form enhances the water solubility and facilitates its incorporation into aqueous systems for experimental purposes. DPPG-Na has been investigated for its potential therapeutic applications in various fields, including drug delivery, pulmonary surfactant replacement, and antimicrobial activity.

Reference

1: Katsai OG, Ruban OA, Krasnopolskyi YM. Preparation and in-vivo evaluation of cytochrome-C-containing liposomes. Pharmazie. 2017 Dec 1;72(12):736-740. doi: 10.1691/ph.2017.7072. PMID: 29441958.