For research use only. Not for therapeutic Use.
Drofenine hydrochloride is a potent competitive inhibitor of BChE, and the ki values of Drofenine is calculated to be 3 uM.
IC50 value: 3 uM (ki)
Target: BChE
Benactyzine is widely used anticholinergic drugs, acts on smooth muscle to stop muscle spasms.
| Catalog Number | I004025 |
| CAS Number | 548-66-3 |
| Synonyms | 2-(diethylamino)ethyl 2-cyclohexyl-2-phenylacetate;hydrochloride |
| Molecular Formula | C20H32ClNO2 |
| Purity | ≥95% |
| InChI | InChI=1S/C20H31NO2.ClH/c1-3-21(4-2)15-16-23-20(22)19(17-11-7-5-8-12-17)18-13-9-6-10-14-18;/h5,7-8,11-12,18-19H,3-4,6,9-10,13-16H2,1-2H3;1H |
| InChIKey | WIELVDXKOYPANK-UHFFFAOYSA-N |
| SMILES | CCN(CC)CCOC(=O)C(C1CCCCC1)C2=CC=CC=C2.Cl |
| Reference | [1]. Bodur E, et al. Inhibition effects of benactyzine and drofenine on human serum butyrylcholinesterase. Arch Biochem Biophys. 2001 Feb 1;386(1):25-29. |
