Drp1-IN-1

• CAT Number: I043730
• CAS Number: 2247733-08-8
• Molecular Formula: C22H24N8OS
• Molecular Weight: 448.54
• Purity: ≥95%
• Synonyms: 4-methyl-1-[(2-piperidin-1-yl-1,3-thiazol-4-yl)methyl]-N-[4-(2H-tetrazol-5-yl)phenyl]pyrrole-2-carboxamide
• InChI: InChI=1S/C22H24N8OS/c1-15-11-19(21(31)23-17-7-5-16(6-8-17)20-25-27-28-26-20)30(12-15)13-18-14-32-22(24-18)29-9-3-2-4-10-29/h5-8,11-12,14H,2-4,9-10,13H2,1H3,(H,23,31)(H,25,26,27,28)
• InChIKey: QNOOJEJAIFNEBQ-UHFFFAOYSA-N
• SMILES: CC1=CN(C(=C1)C(=O)NC2=CC=C(C=C2)C3=NNN=N3)CC4=CSC(=N4)N5CCCCC5

Drp1-IN-1 (comp A-7) is a dynamin-1-like protein (Drp1) inhibitor, with an IC50 of 0.91 μM[1].

Reference

[1]. JI NAN (US), et al. DYNAMIN-1-LIKE PROTEIN INHIBITORS. Patent WO2018200674A1.