DS 4574

• CAT Number: I026550
• CAS Number: 118314-35-5
• Molecular Formula: C13H16N6OS
• Molecular Weight: 304.37
• Purity: 98%
• Synonyms: DS 4574; DS4574; DS 4574
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: (1,3,4)Thiadiazolo(3,2-a)-1,2,3-triazolo(4,5-d)pyrimidin-9(1H)-one, 6-(2-cyclohexylethyl)-
• InChI: InChI=1S/C13H16N6OS/c20-12-10-11(16-18-15-10)14-13-19(12)17-9(21-13)7-6-8-4-2-1-3-5-8/h8H,1-7H2,(H,15,16,18)
• InChIKey: ASIFEXZWAKYMRM-UHFFFAOYSA-N
• SMILES: O=C1C(NN=N2)=C2N=C3N1N=C(CCC4CCCCC4)S3

DS 4574(CAT: I026550) is a potent peptidoleukotriene receptor antagonist that inhibits the binding of leukotrienes, such as LTC4, LTD4, and LTE4, to their receptors. These leukotrienes are key mediators of inflammation and hypersensitivity reactions, particularly in conditions such as asthma and allergic rhinitis. By blocking leukotriene signaling, DS 4574 reduces bronchoconstriction, vascular permeability, and inflammation, making it a valuable therapeutic agent for hypersensitivity disorders. It is widely used in research to study leukotriene receptor pathways, inflammation mechanisms, and the development of targeted therapies for allergic and inflammatory conditions.