For research use only. Not for therapeutic Use.
DS12881479 is a potent and selective Mnk1 inhibitor with an IC50 value of 21 nM. DS12881479 can be used in cancer research[1].
| Catalog Number | I042887 |
| CAS Number | 2373065-59-7 |
| Synonyms | 1-methyl-N-(5-phenyl-1,3-thiazol-2-yl)piperidine-4-carboxamide |
| Molecular Formula | C16H19N3OS |
| Purity | ≥95% |
| InChI | InChI=1S/C16H19N3OS/c1-19-9-7-13(8-10-19)15(20)18-16-17-11-14(21-16)12-5-3-2-4-6-12/h2-6,11,13H,7-10H2,1H3,(H,17,18,20) |
| InChIKey | BTZKRRFKIKIADV-UHFFFAOYSA-N |
| SMILES | CN1CCC(CC1)C(=O)NC2=NC=C(S2)C3=CC=CC=C3 |
| Reference | [1]. Yumi Matsui, et al. A novel inhibitor stabilizes the inactive conformation of MAPK-interacting kinase 1. Acta Crystallogr F Struct Biol Commun. 2018 Mar 1;74(Pt 3):156-160. |
