For research use only. Not for therapeutic Use.
DS39201083(CAT: I026546) is a novel, potent analgesic with a unique bicyclic skeleton, demonstrating efficacy in pain relief without mu-opioid receptor agonist activity. In preclinical models, DS39201083 exhibited superior analgesic effects compared to conolidine in both the acetic acid-induced writhing test and the formalin test in ddY mice. Its mechanism of action, distinct from traditional opioid pathways, positions it as a promising candidate for pain management with a reduced risk of opioid-related side effects such as addiction and respiratory depression. DS39201083 is particularly relevant in pain research, where it aids in exploring alternative, non-opioid therapeutic strategies for managing acute and chronic pain.
| Catalog Number | I026546 |
| Synonyms | DS39201083; DS-39201083; DS 39201083; DS39201083 sulfate; |
| Molecular Formula | C16H20N2O5S |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 5-methyl-1,4,5,7-tetrahydro-2,5-ethanoazocino[4,3-b]indol-6(3H)-one sulfuric acid |
| InChI | InChI=1S/C16H18N2O.H2O4S/c1-16-6-8-18(9-7-16)10-12-11-4-2-3-5-13(11)17-14(12)15(16)19;1-5(2,3)4/h2-5,17H,6-10H2,1H3;(H2,1,2,3,4) |
| InChIKey | PHMKRJVUZIFDAQ-UHFFFAOYSA-N |
| SMILES | O=C1C(CC2)(C)CCN2CC3=C1NC4=C3C=CC=C4.O=S(O)(O)=O |
