For research use only. Not for therapeutic Use.
DS96432529 is a potent and orally active bone anabolic agent through CDK8 inhibition.
| Catalog Number | I045174 |
| CAS Number | 2871872-79-4 |
| Synonyms | 3-amino-4-[(3S)-3-(2-ethoxyethoxymethyl)piperidin-1-yl]thieno[2,3-b]pyridine-2-carboxamide |
| Molecular Formula | C18H26N4O3S |
| Purity | ≥95% |
| InChI | InChI=1S/C18H26N4O3S/c1-2-24-8-9-25-11-12-4-3-7-22(10-12)13-5-6-21-18-14(13)15(19)16(26-18)17(20)23/h5-6,12H,2-4,7-11,19H2,1H3,(H2,20,23)/t12-/m0/s1 |
| InChIKey | GOAKYBVMJUXOFY-LBPRGKRZSA-N |
| SMILES | CCOCCOCC1CCCN(C1)C2=C3C(=C(SC3=NC=C2)C(=O)N)N |
| Reference | [1]. Saito K, et al. Discovery of 3-amino-4-{(3S)-3-[(2-ethoxyethoxy)methyl]piperidin-1-yl}thieno[2,3-b]pyridine-2-carboxamide (DS96432529): A potent and orally active bone anabolic agent. Bioorg Med Chem Lett. 2021 Dec 15;54:128440. |
