DSP-2230

• CAT Number: I019011
• CAS Number: 1233231-30-5
• Molecular Formula: C20H20F3N5O2
• Molecular Weight: 419.40
• Purity: ≥95%
• Synonyms: (2S)-2-[[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)imidazo[4,5-b]pyridin-2-yl]methylamino]propanamide
• InChI: InChI=1S/C20H20F3N5O2/c1-10(19(24)29)25-9-16-26-15-5-6-17(27-20(15)28(16)11-3-2-4-11)30-12-7-13(21)18(23)14(22)8-12/h5-8,10-11,25H,2-4,9H2,1H3,(H2,24,29)/t10-/m0/s1
• InChIKey: HHXCJIMPEJSJTG-JTQLQIEISA-N
• SMILES: CC(C(=O)N)NCC1=NC2=C(N1C3CCC3)N=C(C=C2)OC4=CC(=C(C(=C4)F)F)F

DSP-2230 is a selective Nav1.7/Nav1.8 blocker[1][2].

Reference

[1]. Bagal SK, et al. Voltage gated sodium channels as drug discovery targets. Channels (Austin). 2015;9(6):360-6.
 [Content Brief]

[2]. Sara Sabina Hadida-Ruah, et al. Sulfonamides as modulators of sodium channels.