For research use only. Not for therapeutic Use.
DSPE-PEG(2000)-Amine(Cat No.:I015318) is a compound commonly employed in the synthesis of solid lipids and thermosensitive liposomal nanoparticles for drug delivery applications, particularly in the field of anticancer therapy. It serves as a key component in the formulation of lipids, imparting stability and controlled release properties to liposomes. The addition of DSPE-PEG(2000)-Amine helps enhance the circulation time of liposomal nanoparticles and allows for targeted delivery of anticancer agents, improving their therapeutic efficacy while minimizing potential side effects. This versatile compound plays a crucial role in the development of innovative drug delivery systems for cancer treatment.
CAS Number | 474922-26-4 |
Molecular Formula | (C₂H₄O)nC₄₄H₈₇N₂O₁₀P.NH₃ |
Purity | ≥95% |
Target | Liposome |
Reference | [1]. Feilong Sun, et al. A Mixed Micelle Formulation for Oral Delivery of Vitamin K. Pharm Res. 2016 Sep;33(9):2168-79.<br>[2]. Brian R Sloat, et al. In Vitro and in Vivo Anti-Tumor Activities of a Gemcitabine Derivative Carried by Nanoparticles. Int J Pharm. 2011 May 16;409(1-2):278-88.<br>[3]. Cangel Pui-yee Chan, et al. Nanocrystal Biolabels With Releasable Fluorophores for Immunoassays. Anal Chem. 2004 Jul 1;76(13):3638-45. |