For research use only. Not for therapeutic Use.
DSPE-PEG-NHS (MW 2000) (Cat No.: I040192) is a polyethylene glycol (PEG)-conjugated lipid derivative commonly used in drug delivery and nanoparticle formulations. It consists of a 2000 Da PEG chain linked to a distearoylphosphatidylethanolamine (DSPE) lipid, which enhances stability and solubility in aqueous environments. The NHS (N-hydroxysuccinimide) ester allows for efficient conjugation to primary amines, enabling the attachment of drugs, proteins, or other biomolecules. This makes DSPE-PEG-NHS a valuable tool in creating targeted therapies, especially in liposomal and nanomedicine applications.
| Purity | ≥95% |
| IUPAC Name | [(2R)-3-[2-[2-[[4-(2,5-dioxopyrrolidin-1-yl)oxy-4-oxobutanoyl]amino]ethoxycarbonylamino]ethoxy-hydroxyphosphoryl]oxy-2-octadecanoyloxypropyl] octadecanoate |
| InChI | 1S/C52H94N3O15P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-49(59)66-43-45(69-50(60)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)44-68-71(63,64)67-42-40-54-52(62)65-41-39-53-46(56)35-38-51(61)70-55-47(57)36-37-48(55)58/h45H,3-44H2,1-2H3,(H,53,56)(H,54,62)(H,63,64)/t45-/m1/s1 |
| InChIKey | WYMXOUDMCBGGBO-WBVITSLISA-N |
| SMILES | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCCNC(=O)OCCNC(=O)CCC(=O)ON1C(=O)CCC1=O)OC(=O)CCCCCCCCCCCCCCCCC |
