DTBHQ

  • CAT Number: T000036
  • CAS Number: 88-58-4
  • Molecular Formula: C14H22O2
  • Molecular Weight: 222.328
  • Purity: ≥95%
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It is a potent inhibitor of Ca2+/Mg2+ – ATPase.

Benzohydroquinone,synthetic
Ca2+ mobilizer: the effect of DTBHQ is to inhibit Ca2+ sequestration by the stores and not to stimulate a Ca2+ efflux pathway, suggesting that its inhibitory effects on microsomal Ca2+-ATPase probably underlies its effects on intracellular Ca2+ stores. In permeabilized rat hepatocytes, a maximal concentration (25 μ


Catalog Number T000036
CAS Number 88-58-4
Synonyms

2,5-ditert-butylbenzene-1,4-diol

Molecular Formula C14H22O2
Purity ≥95%
Target ATPase
Solubility In methanol and organic solvents
Storage Store at RT
IUPAC Name 2,5-ditert-butylbenzene-1,4-diol
InChI InChI=1S/C14H22O2/c1-13(2,3)9-7-12(16)10(8-11(9)15)14(4,5)6/h7-8,15-16H,1-6H3
InChIKey JZODKRWQWUWGCD-UHFFFAOYSA-N
SMILES CC(C)(C)C1=CC(=C(C=C1O)C(C)(C)C)O
Reference

– Oldershaw et al., /2,5-Di-(tert-butyl)-1,4-benzohydroquinone mobilizes inositol 1,4,5-triphosphate-sensitive and -insensitive Ca<sup>2+</sup> stores/ <i>FEBS Lett.,</i> (1990). 274(1-2):214-216<br />
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– Schilling et al., <i>Biochem. J</i>., (1992). 284:521<br />
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– Moore et al., <i>FEBS Lett</i>. (1987). 224:331<br />
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– Wictome et al., <i>FEBS Lett</i>. (1992). 304:109<br />
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– Mason et al., <i>J. Biol. Chem</i>. (1991). 266:20856<br />
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