It is a potent inhibitor of Ca2+/Mg2+ – ATPase.
Benzohydroquinone,synthetic
Ca2+ mobilizer: the effect of DTBHQ is to inhibit Ca2+ sequestration by the stores and not to stimulate a Ca2+ efflux pathway, suggesting that its inhibitory effects on microsomal Ca2+-ATPase probably underlies its effects on intracellular Ca2+ stores. In permeabilized rat hepatocytes, a maximal concentration (25 μ
Catalog Number | T000036 |
CAS Number | 88-58-4 |
Synonyms | 2,5-ditert-butylbenzene-1,4-diol |
Molecular Formula | C14H22O2 |
Purity | ≥95% |
Target | ATPase |
Solubility | In methanol and organic solvents |
Storage | Store at RT |
IUPAC Name | 2,5-ditert-butylbenzene-1,4-diol |
InChI | InChI=1S/C14H22O2/c1-13(2,3)9-7-12(16)10(8-11(9)15)14(4,5)6/h7-8,15-16H,1-6H3 |
InChIKey | JZODKRWQWUWGCD-UHFFFAOYSA-N |
SMILES | CC(C)(C)C1=CC(=C(C=C1O)C(C)(C)C)O |
Reference | – Oldershaw et al., /2,5-Di-(tert-butyl)-1,4-benzohydroquinone mobilizes inositol 1,4,5-triphosphate-sensitive and -insensitive Ca<sup>2+</sup> stores/ <i>FEBS Lett.,</i> (1990). 274(1-2):214-216<br /> |