For research use only. Not for therapeutic Use.
DUN00293(CAT: I026591) is a first-in-class inhibitor of Kallikrein-related peptidase 6 (KLK6), making it a groundbreaking tool in neurobiology research. By selectively inhibiting KLK6 activity, it promotes the differentiation of oligodendrocyte precursor cells (OPCs) into mature oligodendrocytes in vitro. This unique mechanism makes DUN00293 invaluable for studies on myelination, demyelinating diseases, and neural repair. With its high specificity, stability, and reproducibility, it is ideal for in vitro studies aiming to explore therapeutic strategies for multiple sclerosis and other neurodegenerative disorders. DUN00293 offers a novel approach for advancing research in neural regeneration and myelin restoration.
| Catalog Number | I026591 |
| Synonyms | DUN00293; DUN-00293; DUN 00293; KLK6-IN-32; |
| Molecular Formula | C15H17ClN2O2 |
| Purity | 98% |
| Solubility | To be determined |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | N-(4-(aminomethyl)phenyl)-2-hydroxy-4-methylbenzamide hydrochloride |
| InChI | InChI=1S/C15H16N2O2.ClH/c1-10-2-7-13(14(18)8-10)15(19)17-12-5-3-11(9-16)4-6-12;/h2-8,18H,9,16H2,1H3,(H,17,19);1H |
| InChIKey | DXZUMVYKZAXKLA-UHFFFAOYSA-N |
| SMILES | O=C(NC1=CC=C(CN)C=C1)C2=CC=C(C)C=C2O.[H]Cl |
