DUN41875

• CAT Number: I026597
• CAS Number: 1295541-87-5
• Molecular Formula: C17H16F3N5O
• Molecular Weight: 363.34
• Purity: 98%
• Synonyms: SCD1 inhibitor-4; DUN41875; DUN-41875; DUN 41875
• Target: Stearoyl-CoA Desaturase (SCD)
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 5-Methyl-N-(1-methyl-1H-pyrazol-3-yl)-1-[[3-(trifluoromethyl)phenyl]methyl]-1H-imidazole-4-carboxamide
• InChI: InChI=1S/C17H16F3N5O/c1-11-15(16(26)22-14-6-7-24(2)23-14)21-10-25(11)9-12-4-3-5-13(8-12)17(18,19)20/h3-8,10H,9H2,1-2H3,(H,22,23,26)
• InChIKey: DUTKICDSXNUMBM-UHFFFAOYSA-N
• SMILES: O=C(C1=C(C)N(CC2=CC=CC(C(F)(F)F)=C2)C=N1)NC3=NN(C)C=C3

DUN41875 (SCD1 Inhibitor-4)(CAT: I026597) is a potent and orally active inhibitor of stearoyl-CoA desaturase-1 (SCD1), an enzyme critical for the biosynthesis of monounsaturated fatty acids. By targeting SCD1, DUN41875 disrupts lipid metabolism, making it a valuable tool for studying metabolic disorders, including obesity, diabetes, and non-alcoholic fatty liver disease (NAFLD). Additionally, its role in modulating tumor lipid metabolism has drawn attention in cancer research. With high specificity and efficacy, DUN41875 supports preclinical studies and drug discovery efforts aimed at developing novel therapies for metabolic and oncological diseases.