DuP 734

• CAT Number: M117783
• CAS Number: 135135-87-4
• Molecular Formula: C17H23BrFNO
• Molecular Weight: 356.28
• Purity: ≥95%
• Synonyms: DuP 734
• Target: Sigma Receptor
• Storage: -20°C
• IUPAC Name: 2-[1-(cyclopropylmethyl)piperidin-4-yl]-1-(4-fluorophenyl)ethanone;hydrobromide
• InChI: InChI=1S/C17H22FNO.BrH/c18-16-5-3-15(4-6-16)17(20)11-13-7-9-19(10-8-13)12-14-1-2-14;/h3-6,13-14H,1-2,7-12H2;1H
• InChIKey: QLZIAKMYJFJBKA-UHFFFAOYSA-N
• SMILES: C1CC1CN2CCC(CC2)CC(=O)C3=CC=C(C=C3)F.Br

DuP 734（Cat No.:M117783）, also known as rupatadine, is a second-generation antihistamine and PAF antagonist used to treat allergic rhinitis and urticaria. It acts by blocking the histamine H1 receptor and inhibiting the platelet-activating factor (PAF), thereby reducing allergic symptoms. Rupatadine has a long duration of action, allowing for once-daily dosing. It is generally well-tolerated, with side effects including drowsiness, headache, and fatigue reported in some patients. Rupatadine is effective in relieving symptoms of allergic rhinitis and urticaria, making it a valuable option for the management of these conditions.