Dutasteride

• CAT Number: A001014
• CAS Number: 164656-23-9
• Molecular Formula: C27H30F6N2O2
• Molecular Weight: 528.50
• Purity: ≥95%
• Synonyms: 164656-23-9; Avodart; Avolve; GG-745; Duagen
• Target: 5-alpha Reductase
• Solubility: >26.4mg/mL in DMSO
• Storage: -20°C
• IUPAC Name: (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide
• InChI: InChI=1S/C27H30F6N2O2/c1-24-11-9-17-15(4-8-21-25(17,2)12-10-22(36)35-21)16(24)6-7-19(24)23(37)34-20-13-14(26(28,29)30)3-5-18(20)27(31,32)33/h3,5,10,12-13,15-17,19,21H,4,6-9,11H2,1-2H3,(H,34,37)(H,35,36)/t15-,16-,17-,19+,21+,24-,25+/m0/s1
• InChIKey: JWJOTENAMICLJG-QWBYCMEYSA-N
• SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)NC4=C(C=CC(=C4)C(F)(F)F)C(F)(F)F)CC[C@@H]5[C@@]3(C=CC(=O)N5)C

Dutasteride（Cat No.:A001014）is a synthetic 5-alpha-reductase inhibitor used primarily to treat benign prostatic hyperplasia (BPH) by reducing the size of an enlarged prostate. It works by inhibiting both type I and type II 5-alpha-reductase enzymes, which convert testosterone into dihydrotestosterone (DHT), a hormone linked to prostate growth. By lowering DHT levels, dutasteride alleviates symptoms of BPH, such as urinary retention and difficulty urinating. It has also been investigated for its role in treating male pattern baldness. Dutasteride is known for its effectiveness in managing prostate-related conditions.

Reference

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