dutomycin

• CAT Number: M091639
• CAS Number: 146663-67-4
• Molecular Formula: C44H54O17
• Molecular Weight: 854.89
• Purity: ≥95%
• Synonyms: dutomycin
• Storage: Desiccate at +4C
• IUPAC Name: [(2S,3R,4R,6S)-6-[(2R,3S,6S)-6-[[(1S,4aS,12aR)-3-acetyl-4,4a,6,12a-tetrahydroxy-9-methoxy-11-methyl-2,5,7,10-tetraoxo-1,12-dihydrotetracen-1-yl]oxy]-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] (Z,4R)-2,4-dimethylhept-2-enoate
• InChI: InChI=1S/C44H54O17/c1-10-11-18(2)14-19(3)41(52)61-39-23(7)58-29(17-42(39,8)53)59-26-12-13-28(57-22(26)6)60-40-36(49)31(21(5)45)37(50)44(55)38(51)32-24(16-43(40,44)54)20(4)30-33(35(32)48)25(46)15-27(56-9)34(30)47/h14-15,18,22-23,26,28-29,39-40,48,50,53-55H,10-13,16-17H2,1-9H3/b19-14-/t18-,22-,23+,26+,28+,29+,39-,40-,42-,43-,44-/m1/s1
• InChIKey: ZYPYHMZLLIDAAL-WNMWLNICSA-N
• SMILES: CCCC(C)C=C(C)C(=O)OC1C(OC(CC1(C)O)OC2CCC(OC2C)OC3C(=O)C(=C(C4(C3(CC5=C(C6=C(C(=O)C=C(C6=O)OC)C(=C5C4=O)O)C)O)O)O)C(=O)C)C

Dutomycin（Cat No.:M091639） is a cyclic peptide antibiotic produced by the bacterium Streptomyces sp. This compound exhibits strong antibacterial properties, particularly against Gram-positive bacteria. It works by interfering with bacterial cell wall synthesis, a critical process for bacterial growth and survival. Dutomycin’s mechanism involves binding to lipid II, a key precursor in the peptidoglycan layer of bacterial cell walls, thereby preventing proper cell wall construction and leading to bacterial cell death. Due to its potent activity, daptomycin is considered a valuable candidate for developing new treatments against resistant bacterial strains.