DX600

• CAT Number: I047254
• CAS Number: 478188-26-0
• Molecular Formula: C141H185N35O40S2
• Molecular Weight: 3074.32
• Purity: ≥95%
• Storage: 3 years -20°C powder
• SMILES: CC(C)CC1NC(=O)C2CCCN2C(=O)C(CO)NC(=O)C(CSSCC(NC(=O)C(CCCCN)NC(=O)C(CC3=C[NH]C4=C3C=CC=C4)NC(=O)C(CC5=C[NH]C6=C5C=CC=C6)NC(=O)C7CCCN7C(=O)C(CC8=CC=C(O)C=C8)NC(=O)C(CC9=CC=C(O)C=C9)NC(=O)C(CCCNC(N)=N)NC1=O)C(=O)NC(C(C)O)C(=O)NC(CC%10=CC=C(O)C=C%10)C(=O)N%11CCCC%11C(=O)NC(CC(O)=O)C(=O)N%12CCCC%12C(=O)NC(CCC(O)=O)C(=O)NCC(=O)NCC(=O)NCC(N)=O)NC(=O)C(CC%13=CN=C[NH]%13)NC(=O)C(CO)NC(=O)C(CC%14=CC=C(O)C=C%14)NC(=O)C(CC(O)=O)NC(=O)CNC(C)=O

DX600 is a specific inhibitor of angiotensin-converting enzyme 2 (ACE2) that does not cross-react with ACE.

Reference

[1] Karen Liao, et al. J Immunol Methods. 2013 Mar 29;389(1-2):52-60.
[2] Minghao Ye, et al. Hypertension. 2012 Sep;60(3):730-40.