Dynasore

• CAT Number: I003065
• CAS Number: 304448-55-3
• Molecular Formula: C₁₈H₁₄N₂O₄ . H₂O
• Molecular Weight: 322.31
• Purity: ≥95%
• Synonyms: (E)-N/’-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthohydrazide
• Target: Autophagy
• Solubility: 10 mM in DMSO
• Storage: store at -20℃
• IC50: 15 uM
• IUPAC Name: N-[(E)-(3,4-dihydroxyphenyl)methylideneamino]-3-hydroxynaphthalene-2-carboxamide
• InChI: InChI=1S/C18H14N2O4/c21-15-6-5-11(7-17(15)23)10-19-20-18(24)14-8-12-3-1-2-4-13(12)9-16(14)22/h1-10,21-23H,(H,20,24)/b19-10+
• InChIKey: SYNDQCRDGGCQRZ-VXLYETTFSA-N
• SMILES: C1=CC=C2C=C(C(=CC2=C1)C(=O)N/N=C/C3=CC(=C(C=C3)O)O)O

Dynasore（Cat No.:I003065）is a small molecule inhibitor that specifically targets dynamin, a GTPase enzyme involved in vesicular trafficking, particularly endocytosis. By inhibiting dynamin, Dynasore prevents the scission of clathrin-coated vesicles from the plasma membrane, thereby disrupting endocytosis. This makes Dynasore a valuable tool for studying cellular processes related to membrane trafficking, receptor internalization, and signal transduction. It has been used in research to investigate the role of endocytosis in various diseases, including cancer and viral infections. However, further studies are needed to assess its potential therapeutic applications and safety for clinical use.