(E)-10-Hydroxynortriptyline-d3

• CAT Number: S000430
• Molecular Formula: C19H18D3NO
• Molecular Weight: 282.39
• Purity: ≥95%
• IUPAC Name: (2E)-2-[3-(trideuteriomethylamino)propylidene]tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-9-ol
• InChI: InChI=1S/C19H21NO/c1-20-12-6-11-16-15-8-3-2-7-14(15)13-19(21)18-10-5-4-9-17(16)18/h2-5,7-11,19-21H,6,12-13H2,1H3/b16-11+/i1D3
• InChIKey: VAGXZGJKNUNLHK-XGLAJIDCSA-N
• SMILES: CNCCC=C1C2=CC=CC=C2CC(C3=CC=CC=C31)O

(E)-10-Hydroxynortriptyline-d3（Cat No.:S000430） is a deuterated form of (E)-10-hydroxynortriptyline, where three hydrogen atoms are replaced with deuterium. This chemical modification is crucial for increasing the metabolic stability of the compound, enabling detailed pharmacokinetic and metabolic studies. (E)-10-Hydroxynortriptyline is an active metabolite of the antidepressant drug nortriptyline, known for its efficacy in treating major depressive disorders. It plays a significant role in the therapeutic effects of its parent compound. The deuterated version, (E)-10-Hydroxynortriptyline-d3, provides researchers with a tool to better understand the drug’s metabolism and pharmacological mechanisms in the body.