E-4031

• CAT Number: I000513
• CAS Number: 113559-13-0
• Molecular Formula: C21H27N3O3S • 2HCl
• Molecular Weight: 474.44
• Purity: ≥95%
• Synonyms: N-(4-(1-(2-(6-methylpyridin-2-yl)ethyl)piperidine-4-carbonyl)phenyl)methanesulfonamide dihydrochloride
• Target: Potassium Channel
• Solubility: DMSO 50 mg/ml Water 100 mg/ml
• Storage: -20°C
• IUPAC Name: N-[4-[1-[2-(6-methylpyridin-2-yl)ethyl]piperidine-4-carbonyl]phenyl]methanesulfonamide;dihydrochloride
• InChI: InChI=1S/C21H27N3O3S.2ClH/c1-16-4-3-5-19(22-16)12-15-24-13-10-18(11-14-24)21(25)17-6-8-20(9-7-17)23-28(2,26)27;;/h3-9,18,23H,10-15H2,1-2H3;2*1H
• InChIKey: ZQBNWMFBOSOOLX-UHFFFAOYSA-N
• SMILES: CC1=NC(=CC=C1)CCN2CCC(CC2)C(=O)C3=CC=C(C=C3)NS(=O)(=O)C.Cl.Cl

E-4031（Cat No.:113559-13-0） is an antiarrhythmic agent belonging to the benzenesulfonamide class. It functions by blocking the ATP-sensitive potassium channel. By inhibiting this channel, E-4031 disrupts the flow of potassium ions, prolonging the action potential duration in cardiac cells. This property makes it useful in the treatment of certain cardiac arrhythmias. E-4031’s mechanism of action and specific target make it valuable in studying potassium channel function and developing therapeutic interventions for arrhythmias and related cardiovascular disorders.