(E)-[6]-Dehydroparadol

• CAT Number: I013738
• CAS Number: 878006-06-5
• Molecular Formula: C₁₇H₂₄O₃
• Molecular Weight: 276.37
• Purity: ≥95%
• Target: NF-κB
• Solubility: DMSO: ≥ 140 mg/mL
• Storage: Store at -20°C
• IUPAC Name: (E)-1-(4-hydroxy-3-methoxyphenyl)dec-1-en-3-one
• InChI: InChI=1S/C17H24O3/c1-3-4-5-6-7-8-15(18)11-9-14-10-12-16(19)17(13-14)20-2/h9-13,19H,3-8H2,1-2H3/b11-9+
• InChIKey: AXMBOMODZLJDKX-PKNBQFBNSA-N
• SMILES: CCCCCCCC(=O)C=CC1=CC(=C(C=C1)O)OC

(E)-[6]-Dehydroparadol（Cat No.:I013738）, identified as compound M15 in patent US 9272994, demonstrates growth inhibition and induction of apoptosis in human cancer cells. It exhibits IC50 values of 43.02 μM in HCT-116 cells and 41.59 μM in H-1299 cells, indicating its potency against these cell lines. These findings suggest the potential of (E)-[6]-Dehydroparadol as a promising candidate for further exploration and development as an anti-cancer agent, although additional research and studies are required to assess its efficacy and safety in vivo.