E-64c

• CAT Number: R060889
• CAS Number: 76684-89-4
• Molecular Formula: C15H26N2O5
• Molecular Weight: 314.38
• Purity: ≥95%
• Synonyms: Loxistatin acid; NSC 694279; (2S,3S)-3-[[[(1S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]oxiranecarboxylic Acid; [2S-[2α,3β(R*)]]-3-[[[3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]oxiranecarboxylic Acid; Ep 47
• Target: Anti-infection
• Solubility: Soluble in DMSO > 10 mM
• Storage: Store at -20°C
• IUPAC Name: (2S,3S)-3-[[(2S)-4-methyl-1-(3-methylbutylamino)-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid
• InChI: InChI=1S/C15H26N2O5/c1-8(2)5-6-16-13(18)10(7-9(3)4)17-14(19)11-12(22-11)15(20)21/h8-12H,5-7H2,1-4H3,(H,16,18)(H,17,19)(H,20,21)/t10-,11-,12-/m0/s1
• InChIKey: SCMSYZJDIQPSDI-SRVKXCTJSA-N
• SMILES: CC(C)CCNC(=O)C(CC(C)C)NC(=O)C1C(O1)C(=O)O

E 64c（Cat No.:R060889）is a synthetic compound derived from natural epoxide inhibitors of cysteine proteases. It acts as an inhibitor of calcium-activated neutral protease (CANP) and possesses weak irreversible inhibitory activity against cathepsin C. As a cysteine protease inhibitor, E 64c interferes with the function of specific enzymes involved in cellular processes, making it valuable in research related to proteolytic pathways and cellular regulation. Its selective inhibition of proteases holds potential in therapeutic development for various diseases where cysteine proteases play crucial roles.