(E)-LHF-535

For research use only. Not for therapeutic Use.

  • CAT Number: I046208
  • Molecular Formula: C27H28N2O2
  • Molecular Weight: 412.52
  • Purity: ≥95%
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(E)-LHF-535 is the E-isomer of LHF-535. LHF-535 is an antiviral agent extracted from patent WO2013123215A2, Compound 38, has EC50s of <1 μM, <1 μM, <1 μM, and 1-10 μM for Lassa, Machupo, Junin, and VSVg virus, respectively[1].


Catalog Number I046208
Synonyms

2-[4-[(E)-2-[1-(4-propan-2-yloxyphenyl)benzimidazol-5-yl]ethenyl]phenyl]propan-2-ol

Molecular Formula C27H28N2O2
Purity ≥95%
InChI InChI=1S/C27H28N2O2/c1-19(2)31-24-14-12-23(13-15-24)29-18-28-25-17-21(9-16-26(25)29)6-5-20-7-10-22(11-8-20)27(3,4)30/h5-19,30H,1-4H3/b6-5+
InChIKey DBNZTRPIBJSUIX-AATRIKPKSA-N
SMILES CC(C)OC1=CC=C(C=C1)N2C=NC3=C2C=CC(=C3)C=CC4=CC=C(C=C4)C(C)(C)O
Reference

[1]. Dongcheng Dai, et al. Antiviral drugs for treatment of arenavirus infection. WO2013123215A2.

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