For research use only. Not for therapeutic Use.
(E)-Naftifine(CAT: C000288) is a pharmaceutical compound primarily employed in dermatology. Its mechanism of action involves inhibiting the biosynthesis of ergosterol in fungal cell membranes, making it an effective antifungal agent. This property makes it an essential ingredient in topical treatments for various fungal skin infections. Additionally, (E)-Naftifine has found application in organic chemistry as a synthetic building block, contributing to the creation of molecules with diverse structures. Its significance lies in its role in pharmaceuticals for treating skin conditions and its contribution to the field of organic chemistry as a versatile reagent.
| Catalog Number | C000288 |
| CAS Number | 65472-88-0 |
| Synonyms | N-Methyl-N-[(2E)-3-phenyl-2-propen-1-yl]-1-naphthalenemethanamine |
| Molecular Formula | C₂₁H₂₁N |
| Purity | ≥95% |
| Solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Very |
| Appearance | Colourless to Dark Yellow Thick Oil |
| Storage | 4°C |
| Reference | Georgopoulos, A., et al.: Antimicrob. Ag. Chemother., 19, 386 (1981); Meingassner, J.C., et al.: J. Invest. Dermatol., 77, 444 (1981); Paltauf, F., et al.: Biochim Biophys. Acta, 712, 268 (1982); Aggarwal, D., et al.: J. Pharm. Pharmacol., 56, 1509 (2004) |
