E3 ligase Ligand 23

For research use only. Not for therapeutic Use.

  • CAT Number: I043866
  • CAS Number: 444287-56-3
  • Molecular Formula: C20H17N3O4
  • Molecular Weight: 363.37
  • Purity: ≥95%
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E3 ligase Ligand 23 (compound 17-6) is a cereblon binder for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway[1].


Catalog Number I043866
CAS Number 444287-56-3
Synonyms

4-(benzylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione

Molecular Formula C20H17N3O4
Purity ≥95%
InChI InChI=1S/C20H17N3O4/c24-16-10-9-15(18(25)22-16)23-19(26)13-7-4-8-14(17(13)20(23)27)21-11-12-5-2-1-3-6-12/h1-8,15,21H,9-11H2,(H,22,24,25)
InChIKey JBYQCGLMICPOSQ-UHFFFAOYSA-N
SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCC4=CC=CC=C4
Reference

[1]. Gesine Kerstin VEITS, et al. Cereblon binders for the degradation of ikaros. WO2019191112A1.

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