For research use only. Not for therapeutic Use.
E3 ligase Ligand 23 (compound 17-6) is a cereblon binder for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway[1].
Catalog Number | I043866 |
CAS Number | 444287-56-3 |
Synonyms | 4-(benzylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione |
Molecular Formula | C20H17N3O4 |
Purity | ≥95% |
InChI | InChI=1S/C20H17N3O4/c24-16-10-9-15(18(25)22-16)23-19(26)13-7-4-8-14(17(13)20(23)27)21-11-12-5-2-1-3-6-12/h1-8,15,21H,9-11H2,(H,22,24,25) |
InChIKey | JBYQCGLMICPOSQ-UHFFFAOYSA-N |
SMILES | C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCC4=CC=CC=C4 |
Reference | [1]. Gesine Kerstin VEITS, et al. Cereblon binders for the degradation of ikaros. WO2019191112A1. |