E3 ligase Ligand-Linker Conjugates 14

• CAT Number: I013190
• CAS Number: 1957236-21-3
• Molecular Formula: C₂₅H₃₁F₃N₄O₁₁
• Molecular Weight: 620.53
• Purity: ≥95%
• Target: E3 Ligase Ligand-Linker Conjugate
• Solubility: DMSO
• IUPAC Name: N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C23H30N4O9.C2HF3O2/c24-6-8-33-10-12-35-13-11-34-9-7-25-19(29)14-36-17-3-1-2-15-20(17)23(32)27(22(15)31)16-4-5-18(28)26-21(16)30;3-2(4,5)1(6)7/h1-3,16H,4-14,24H2,(H,25,29)(H,26,28,30);(H,6,7)
• InChIKey: BLYRZYHKZRITLJ-UHFFFAOYSA-N
• SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)NCCOCCOCCOCCN.C(=O)(C(F)(F)F)O

E3 ligase Ligand-Linker Conjugates 14 (Cat.No:I013190) is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology.

Reference

[1]. WO/2017/024317A2