E3 ligase Ligand-Linker Conjugates 17

• CAT Number: I013187
• CAS Number: 1950635-16-1
• Molecular Formula: C₂₅H₃₁F₃N₄O₈
• Molecular Weight: 572.53
• Purity: ≥95%
• Target: Autophagy
• Solubility: DMSO
• IUPAC Name: N-(8-aminooctyl)-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C23H30N4O6.C2HF3O2/c24-12-5-3-1-2-4-6-13-25-19(29)14-33-17-9-7-8-15-20(17)23(32)27(22(15)31)16-10-11-18(28)26-21(16)30;3-2(4,5)1(6)7/h7-9,16H,1-6,10-14,24H2,(H,25,29)(H,26,28,30);(H,6,7)
• InChIKey: AJVLNIUPDHKOPS-UHFFFAOYSA-N
• SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)NCCCCCCCCN.C(=O)(C(F)(F)F)O

E3 ligase Ligand-Linker Conjugates 17 (CAT: I013187) are selective compounds designed to recruit E3 ligases to specific protein targets for degradation. They consist of a ligand, linker, and E3 ligase recruiting moiety. By utilizing these conjugates, targeted protein degradation can be achieved, offering potential therapeutic applications for diseases involving protein dysregulation. E3 ligase Ligand-Linker Conjugates 17 exemplify this class of compounds, contributing to the advancement of targeted protein degradation strategies.