E3 Ligase Ligand-Linker Conjugates 2

• CAT Number: I013140
• CAS Number: 1818885-63-0
• Molecular Formula: C₂₇H₃₂N₄O₈
• Molecular Weight: 540.57
• Purity: ≥95%
• Target: E3 Ligase Ligand-Linker Conjugate
• Solubility: DMSO
• IUPAC Name: 4-[2-[2-[2-[2-(4-aminophenoxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
• InChI: InChI=1S/C27H32N4O8/c28-18-4-6-19(7-5-18)39-17-16-38-15-14-37-13-12-36-11-10-29-21-3-1-2-20-24(21)27(35)31(26(20)34)22-8-9-23(32)30-25(22)33/h1-7,22,29H,8-17,28H2,(H,30,32,33)
• InChIKey: QTFDOBJYFQFDIO-UHFFFAOYSA-N
• SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCOCCOC4=CC=C(C=C4)N

E3 Ligase Ligand-Linker Conjugates 2(CAT: I013140) is a compound designed for use in the synthesis of PROTACs. This conjugate consists of an E3 ligase ligand connected to a linker molecule. PROTACs are bifunctional molecules that recruit specific target proteins to E3 ligases, leading to ubiquitination and subsequent degradation of the target by the proteasome. E3 Ligase Ligand-Linker Conjugates 2 can serve as a key component in the development of PROTACs, enabling the targeted degradation of disease-associated proteins and offering a novel approach for therapeutic intervention in various diseases.