For research use only. Not for therapeutic Use.
E4CPG(CAT: I002231) is a potent and selective antagonist of metabotropic glutamate receptors (mGluRs), specifically targeting group I mGluRs (mGlu1 and mGlu5). By inhibiting these receptors, E4CPG modulates glutamatergic neurotransmission, reducing excitatory signaling in the central nervous system. This mechanism makes E4CPG a valuable tool in neurological research, particularly in studying neurodegenerative diseases, epilepsy, and chronic pain. Its ability to regulate glutamate pathways helps in exploring therapeutic strategies for conditions associated with excessive neuronal excitation and excitotoxicity.
| Catalog Number | I002231 |
| CAS Number | 170846-89-6 |
| Synonyms | (S)-4-(1-amino-1-carboxypropyl)benzoic acid |
| Molecular Formula | C11H13NO4 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | Soluble to 100 mM in 1.1eq. NaOH |
| Storage | Store at RT |
| IUPAC Name | 4-(1-amino-1-carboxypropyl)benzoic acid |
| InChI | InChI=1S/C11H13NO4/c1-2-11(12,10(15)16)8-5-3-7(4-6-8)9(13)14/h3-6H,2,12H2,1H3,(H,13,14)(H,15,16) |
| InChIKey | AIEFWRHRHFRLFT-UHFFFAOYSA-N |
| SMILES | CCC(C1=CC=C(C=C1)C(=O)O)(C(=O)O)N |
