For research use only. Not for therapeutic Use.
E7107 is a first-in-class precursor messenger ribonucleic acid (pre-mRNA) spliceosome inhibitor.
| Catalog Number | I026658 |
| CAS Number | 630100-90-2 |
| Synonyms | E7107; E-7107; E 7107; |
| Molecular Formula | C40H66N2O9 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | [(2S,3S,4E,6S,7R,10R)-7,10-Dihydroxy-2-[(2E,4E,6R)-6-hydroxy-7-[(2R,3R)-3-[(2R,3S)-3-hydroxypentan-2-yl]oxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-3,7-dimethyl-12-oxo-1-oxacyclododec-4-en-6-yl] 4-cycloheptylpiperazine-1-carboxylate |
| InChI | InChI=1S/C40H66N2O9/c1-7-32(44)29(4)37-33(49-37)26-39(5,47)19-12-13-27(2)36-28(3)16-17-34(40(6,48)20-18-31(43)25-35(45)51-36)50-38(46)42-23-21-41(22-24-42)30-14-10-8-9-11-15-30/h12-13,16-17,19,28-34,36-37,43-44,47-48H,7-11,14-15,18,20-26H2,1-6H3/b17-16+,19-12+,27-13+/t28-,29+,31+,32-,33+,34-,36+,37+,39-,40+/m0/s1 |
| InChIKey | MNOMBFWMICHMKG-MGYWSNOQSA-N |
| SMILES | O=C(N1CCN(C2CCCCCC2)CC1)O[C@H]([C@](C)(O)CC[C@@H](O)C3)/C=C/[C@H](C)[C@@H](/C(C)=C/C=C/[C@](C)(O)C[C@H]4O[C@@H]4[C@@H]([C@@H](O)CC)C)OC3=O |
