For research use only. Not for therapeutic Use.
Potent aldose reductase inhibitor
| Catalog Number | R053725 |
| CAS Number | 4450-98-0 |
| Molecular Formula | C14H15NO4 |
| Purity | ≥95% |
| IUPAC Name | ethyl 1-benzyl-4-hydroxy-5-oxo-2H-pyrrole-3-carboxylate |
| InChI | InChI=1S/C14H15NO4/c1-2-19-14(18)11-9-15(13(17)12(11)16)8-10-6-4-3-5-7-10/h3-7,16H,2,8-9H2,1H3 |
| SMILES | CCOC(=O)C1=C(C(=O)N(C1)CC2=CC=CC=C2)O |
| Reference | EK Lee et al. Inhibition of aldose reductase enhances HeLa cell sensitivity to chemotherapeutic drugs and involves activation of extracellular signal-regulated kinases. Anti-Cancer Drugs. 2002, 13(8), 859-868.
BL Mylari et al. A highly specific aldose reductase inhibitor, ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate and its congeners. J. Med. Chem. 1991, 34, 1011. |
