For research use only. Not for therapeutic Use.
EC-17 (disodium salt)(CAT: I020000) is a fluorescent contrast agent specifically designed to target folate receptor alpha (FRα), which is overexpressed in various cancers, including ovarian, lung, and breast cancers. Its fluorescent properties in the visible light spectrum enable real-time imaging and tumor localization during diagnostic and surgical procedures. By selectively binding to FRα, EC-17 enhances visualization of cancerous tissues while sparing normal cells. This compound is widely utilized in oncology research for studying FRα expression, tumor detection, and the development of targeted imaging strategies, offering a non-invasive and precise tool for cancer diagnostics and intraoperative guidance.
Catalog Number | I020000 |
CAS Number | 910661-33-5 |
Molecular Formula | C42H38N10NaO10S |
Purity | ≥95% |
IUPAC Name | [HH].C1=CC(=CC=C1C(=O)N[C@@H](CCC(=O)NCCNC(=S)NC2=CC3=C(C=C2)C4(C5=C(C=C(C=C5)O)OC6=C4C=CC(=C6)O)OC3=O)C(=O)O)NCC7=CN=C8C(=N7)C(=O)NC(=N8)N.[Na] |
InChI | InChI=1S/C42H36N10O10S.Na.H2/c43-40-51-35-34(37(57)52-40)48-23(19-47-35)18-46-21-3-1-20(2-4-21)36(56)50-30(38(58)59)11-12-33(55)44-13-14-45-41(63)49-22-5-8-27-26(15-22)39(60)62-42(27)28-9-6-24(53)16-31(28)61-32-17-25(54)7-10-29(32)42;;/h1-10,15-17,19,30,46,53-54H,11-14,18H2,(H,44,55)(H,50,56)(H,58,59)(H2,45,49,63)(H3,43,47,51,52,57);;1H/t30-;;/m0../s1 |
InChIKey | LHFHTILJSBWECG-ARIINYJRSA-N |
SMILES | [HH].C1=CC(=CC=C1C(=O)N[C@@H](CCC(=O)NCCNC(=S)NC2=CC3=C(C=C2)C4(C5=C(C=C(C=C5)O)OC6=C4C=CC(=C6)O)OC3=O)C(=O)O)NCC7=CN=C8C(=N7)C(=O)NC(=N8)N.[Na] |