Echitamine chloride

• CAT Number: I015299
• CAS Number: 6878-36-0
• Molecular Formula: C₂₂H₂₉ClN₂O₄
• Molecular Weight: 420.93
• Purity: ≥95%
• Target: Apoptosis
• Storage: 4°C, protect from light
• IUPAC Name: methyl (13Z)-13-ethylidene-10-hydroxy-18-(hydroxymethyl)-15-methyl-8-aza-15-azoniapentacyclo[10.5.1.01,9.02,7.09,15]octadeca-2,4,6-triene-18-carboxylate
• InChI: InChI=1S/C22H29N2O4/c1-4-14-12-24(2)10-9-21-15-7-5-6-8-17(15)23-22(21,24)18(26)11-16(14)20(21,13-25)19(27)28-3/h4-8,16,18,23,25-26H,9-13H2,1-3H3/q+1/b14-4+
• InChIKey: AFJPGVUCVDCFPM-LNKIKWGQSA-N
• SMILES: CC=C1C[N+]2(CCC34C2(C(CC1C3(CO)C(=O)OC)O)NC5=CC=CC=C45)C

Echitamine chloride（Cat No.:I015299） is a significant monoterpene indole alkaloid found in Alstonia plants. It possesses potent antitumor activity by inducing DNA fragmentation and apoptosis, which leads to the suppression of tumor growth. Additionally, Echitamine chloride exhibits inhibitory effects on pancreatic lipase, an enzyme involved in fat digestion, with an IC50 value of 10.92 µM. These findings suggest the potential of Echitamine chloride as an anticancer agent and as a therapeutic option for conditions related to pancreatic lipase activity.