For research use only. Not for therapeutic Use.
Econazole Nitrate(Cat No.:A000795)is an antifungal agent used primarily in the treatment of dermatophyte infections, including athlete’s foot, ringworm, and candidiasis. It works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting the integrity of the cell membrane and causing fungal cell death. This imidazole derivative is topically applied and is effective against a broad spectrum of fungal pathogens. Econazole Nitrate is commonly found in cream, ointment, and solution formulations, offering a reliable solution for localized skin infections.
Catalog Number | A000795 |
CAS Number | 24169-02-6 |
Synonyms | 24169-02-6; Ifenec; Epi-pevaryl; Gyno-pevaryl; Pevaryl |
Molecular Formula | C18H16Cl3N3O4 |
Purity | ≥95% |
Target | Fungal |
Storage | -20°C |
IUPAC Name | 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole;nitric acid |
InChI | InChI=1S/C18H15Cl3N2O.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4) |
InChIKey | DDXORDQKGIZAME-UHFFFAOYSA-N |
SMILES | C1=CC(=CC=C1COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-] |
Reference | 1: Shah RM, Eldridge DS, Palombo EA, Harding IH. Microwave-assisted microemulsion 2: Abd El-Gawad AEH, Soliman OA, El-Dahan MS, Al-Zuhairy SAS. Improvement of the 3: Suñer-Carbó J, Boix-Montañés A, Halbaut-Bellowa L, Velázquez-Carralero N, 4: Fleischer AB Jr, Raymond I. Econazole Nitrate Foam 1% Improves the Itch of <br> 6: Ren Y, Zhang Q, Yu Z. [Clinical analysis of external ear canal coating by 7: Sun J, Yu CH, Zhao XL, Wang Y, Jiang SG, Gong XF. Econazole Nitrate Induces 8: Chen Z, Li X, Wu X, Wang W, Wang W, Xin M, Shen F, Liu L, Liang J, Li L, Yu L. <br> 10: Gajra B, Pandya SS, Singh S, Rabari HA. Mucoadhesive hydrogel films of |