For research use only. Not for therapeutic Use.
Edecesertib (Cat No.:I043411) is an experimental small molecule inhibitor targeting STAT3 (Signal Transducer and Activator of Transcription 3), a key protein involved in the regulation of immune responses and cancer cell survival. By blocking STAT3 activity, Edecesertib aims to disrupt tumor growth and enhance immune system response, making it a promising candidate in cancer immunotherapy. Currently undergoing clinical trials, this compound has shown potential in treating various cancers, including lymphoma and solid tumors, by inhibiting tumor progression and promoting anti-cancer immunity. Further studies are needed to evaluate its efficacy and safety.
| CAS Number | 2408839-73-4 |
| Synonyms | 4-[[(1R)-1-cyanoethyl]amino]-6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-N-[(2R)-2-fluoro-3-hydroxy-3-methylbutyl]pyridine-3-carboxamide |
| Molecular Formula | C22H22FN7O2 |
| Purity | ≥95% |
| IUPAC Name | 4-[[(1R)-1-cyanoethyl]amino]-6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-N-[(2R)-2-fluoro-3-hydroxy-3-methylbutyl]pyridine-3-carboxamide |
| InChI | InChI=1S/C22H22FN7O2/c1-13(8-24)29-17-7-18(19-5-4-15-6-14(9-25)10-28-30(15)19)26-11-16(17)21(31)27-12-20(23)22(2,3)32/h4-7,10-11,13,20,32H,12H2,1-3H3,(H,26,29)(H,27,31)/t13-,20-/m1/s1 |
| InChIKey | HORBHQPSWJRDSV-ZUOKHONESA-N |
| SMILES | C[C@H](C#N)NC1=CC(=NC=C1C(=O)NC[C@H](C(C)(C)O)F)C2=CC=C3N2N=CC(=C3)C#N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
