Edonentan Hydrate

• CAT Number: R059608
• CAS Number: 264609-13-4
• Molecular Formula: C28H34N4O6S
• Molecular Weight: 554.662
• Purity: ≥95%
• Synonyms: N-[[2’-[[(4,5-Dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1’-biphenyl]-2-yl]methyl]-N,3,3-trimethylbutanamide Monohydrate; BMS 207940 Hydrate
• Target: Endothelin Receptor
• Storage: Store at +4 ℃
• IUPAC Name: N-[[2-[2-[(4,5-dimethyl-1,2-oxazol-3-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N,3,3-trimethylbutanamide;hydrate
• InChI: InChI=1S/C28H32N4O5S.H2O/c1-18-19(2)37-30-26(18)31-38(34,35)24-10-8-7-9-23(24)22-12-11-20(27-29-13-14-36-27)15-21(22)17-32(6)25(33)16-28(3,4)5;/h7-15H,16-17H2,1-6H3,(H,30,31);1H2
• InChIKey: VRUJTPHFVRXEPB-UHFFFAOYSA-N
• SMILES: CC1=C(ON=C1NS(=O)(=O)C2=CC=CC=C2C3=C(C=C(C=C3)C4=NC=CO4)CN(C)C(=O)CC(C)(C)C)C.O

Edonentan hydrate is a pharmaceutical compound developed as an endothelin receptor antagonist. It specifically targets endothelin receptors, which are involved in vasoconstriction, making it potentially useful in the treatment of pulmonary arterial hypertension and other cardiovascular diseases characterized by elevated blood pressure in the arteries of the lungs. By blocking the action of endothelins, substances that cause blood vessels to constrict, edonentan hydrate aims to decrease vascular resistance, thereby improving cardiac function and reducing blood pressure.