For research use only. Not for therapeutic Use.
Edonerpic maleate (Cat.No:I013054) is a novel compound under investigation for its potential cognitive-enhancing effects. It acts as a selective 5-HT6 receptor agonist, targeting specific receptors in the brain associated with memory and learning. Studies suggest that Edonerpic maleate may have therapeutic implications in treating cognitive disorders, such as Alzheimer’s disease.
| Catalog Number | I013054 |
| CAS Number | 519187-97-4 |
| Molecular Formula | C₂₀H₂₅NO₆S |
| Purity | ≥95% |
| Target | Amyloid-β |
| Solubility | DMSO: 155 mg/mL |
| IUPAC Name | 1-[3-[2-(1-benzothiophen-5-yl)ethoxy]propyl]azetidin-3-ol;(Z)-but-2-enedioic acid |
| InChI | InChI=1S/C16H21NO2S.C4H4O4/c18-15-11-17(12-15)6-1-7-19-8-4-13-2-3-16-14(10-13)5-9-20-16;5-3(6)1-2-4(7)8/h2-3,5,9-10,15,18H,1,4,6-8,11-12H2;1-2H,(H,5,6)(H,7,8)/b;2-1- |
| InChIKey | RLUCYBFCLXANSO-BTJKTKAUSA-N |
| SMILES | C1C(CN1CCCOCCC2=CC3=C(C=C2)SC=C3)O.C(=CC(=O)O)C(=O)O |
| Reference | [1]. Hirata K, et al. A novel neurotrophic agent, T-817MA [1-{3-[2-(1-benzothiophen-5-yl) ethoxy] propyl}-3-azetidinol maleate], attenuates amyloid-beta-induced neurotoxicity and promotes neurite outgrowth in rat cultured central nervous system neurons. J Pharmacol Exp Ther. 2005 Jul;314(1):252-9.<br>[2]. Kimura T, et al. T-817MA, a neurotrophic agent, ameliorates the deficits in adult neurogenesis and spatial memory in rats infused i.c.v. with amyloid-beta peptide. Br J Pharmacol. 2009 Jun;157(3):451-63. |
