Edoxaban tosylate monohydrate

• CAT Number: I006593
• CAS Number: 1229194-11-9
• Molecular Formula: C31H40ClN7O8S2
• Molecular Weight: 738.27
• Purity: ≥95%
• Synonyms: DU176b; DU-176b; DU 176b; Edoxaban; Edoxaban tosylate monohydrate, trade name Lixiana.;N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide 4-methylbe
• Target: factor Xa inhibitor
• Solubility: Soluble in DMSO.
• Storage: 0 - 4°C for short term or -20 °C for long term
• IUPAC Name: N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide;4-methylbenzenesulfonic acid;hydrate
• InChI: InChI=1S/C24H30ClN7O4S.C7H8O3S.H2O/c1-31(2)24(36)13-4-6-15(27-20(33)21(34)30-19-7-5-14(25)11-26-19)17(10-13)28-22(35)23-29-16-8-9-32(3)12-18(16)37-23;1-6-2-4-7(5-3-6)11(8,9)10;/h5,7,11,13,15,17H,4,6,8-10,12H2,1-3H3,(H,27,33)(H,28,35)(H,26,30,34);2-5H,1H3,(H,8,9,10);1H2/t13-,15-,17+;;/m0../s1
• InChIKey: PSMMNJNZVZZNOI-SJILXJHISA-N
• SMILES: CC1=CC=C(C=C1)S(=O)(=O)O.CN1CCC2=C(C1)SC(=N2)C(=O)N[C@@H]3C[C@H](CC[C@@H]3NC(=O)C(=O)NC4=NC=C(C=C4)Cl)C(=O)N(C)C.O

Edoxaban Tosylate Monohydrate(CAT: I006593) is an oral, selective, and reversible direct inhibitor of Factor Xa, a key enzyme in the coagulation cascade. By blocking Factor Xa, it prevents the conversion of prothrombin to thrombin, reducing clot formation. This compound is particularly valuable in cardiovascular research, supporting studies on thrombosis, stroke prevention, and atrial fibrillation. Edoxaban Tosylate Monohydrate provides a reliable tool for exploring anticoagulation mechanisms and developing novel therapies for thromboembolic disorders. Its high specificity and efficacy make it integral to advancing research in hemostasis and anticoagulant drug development.