For research use only. Not for therapeutic Use.
Edralbrutinib (TG-1701) is a potent BTK inhibitor[1].
| Catalog Number | I026719 |
| CAS Number | 1858206-58-2 |
| Synonyms | 4-amino-1-[(3R)-1-but-2-ynoylpyrrolidin-3-yl]-3-[4-(2,6-difluorophenoxy)phenyl]-6H-pyrrolo[2,3-d]pyridazin-7-one |
| Molecular Formula | C26H21F2N5O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C26H21F2N5O3/c1-2-4-21(34)32-12-11-16(13-32)33-14-18(22-23(33)26(35)31-30-25(22)29)15-7-9-17(10-8-15)36-24-19(27)5-3-6-20(24)28/h3,5-10,14,16H,11-13H2,1H3,(H2,29,30)(H,31,35)/t16-/m1/s1 |
| InChIKey | DNPOFZXZJJDQLB-MRXNPFEDSA-N |
| SMILES | CC#CC(=O)N1CCC(C1)N2C=C(C3=C2C(=O)NN=C3N)C4=CC=C(C=C4)OC5=C(C=CC=C5F)F |
| Reference | [1]. JIANGSU HENGRUI MEDICINE CO, et al. Pharmaceutically acceptable salt and crystal form of pyrrolo[2,3-d]pyridazin-7-one derivative and preparation method of medicinal salt and crystal form. WO2018210296A1. |
