(E,E)-Bis(2-hydroxybenzylidene)acetone(2-HBA)

• CAT Number: R059784
• CAS Number: 131359-24-5
• Molecular Formula: C17H14O3
• Molecular Weight: 266.29
• Purity: ≥95%
• Synonyms: (1E,4E)-1,5-Bis(2-hydroxyphenyl)-1,4-pentadien-3-one; 2-HBA; (E,E)-1,5-Bis(2-hydroxyphenyl)-1,4-pentadien-3-one
• Target: Caspase
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: (1E,4E)-1,5-bis(2-hydroxyphenyl)penta-1,4-dien-3-one
• InChI: InChI=1S/C17H14O3/c18-15(11-9-13-5-1-3-7-16(13)19)12-10-14-6-2-4-8-17(14)20/h1-12,19-20H/b11-9+,12-10+
• InChIKey: YNVAHBUBGBLIEY-WGDLNXRISA-N
• SMILES: C1=CC=C(C(=C1)/C=C/C(=O)/C=C/C2=CC=CC=C2O)O

(E,E)-Bis(2-hydroxybenzylidene)acetone (2-HBA)（Cat No.:R059784）is a synthetic compound with a unique chalcone-like structure, widely studied for its pharmacological properties. It exhibits potent antioxidant, anti-inflammatory, and anticancer activities, making it valuable in biomedical research. 2-HBA interacts with cellular signaling pathways, such as NF-κB and apoptosis-related mechanisms, contributing to its therapeutic potential in cancer and chronic inflammatory diseases. Additionally, its ability to chelate metal ions highlights its role in combating oxidative stress. 2-HBA serves as a key tool in exploring structure-activity relationships and developing novel therapeutic agents.