For research use only. Not for therapeutic Use.
EGCG Octaacetate（Cat No.:I017922）is a derivative of epigallocatechin gallate (EGCG), a key polyphenol found in green tea. This compound is acetylated at all eight hydroxyl groups, enhancing its stability and lipophilicity. EGCG Octaacetate exhibits potent antioxidant, anti-inflammatory, and anticancer properties, making it useful in pharmacological research. Its ability to modulate cellular pathways, such as those involved in oxidative stress and inflammation, positions it as a promising candidate for therapeutic development, especially in cancer and neurodegenerative diseases. It also offers potential in cosmetics for its skin-protective benefits.
| Catalog Number | I017922 |
| CAS Number | 148707-39-5 |
| Molecular Formula | C₃₈H₃₄O₁₉ |
| Purity | ≥95% |
| Target | Bacterial |
| IUPAC Name | [(2R,3R)-5,7-diacetyloxy-2-(3,4,5-triacetyloxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-triacetyloxybenzoate |
| InChI | InChI=1S/C38H34O19/c1-16(39)48-26-13-28(49-17(2)40)27-15-34(57-38(47)25-11-32(52-20(5)43)37(55-23(8)46)33(12-25)53-21(6)44)35(56-29(27)14-26)24-9-30(50-18(3)41)36(54-22(7)45)31(10-24)51-19(4)42/h9-14,34-35H,15H2,1-8H3/t34-,35-/m1/s1 |
| InChIKey | SVHJCTSSYQPWEV-VSJLXWSYSA-N |
| SMILES | CC(=O)OC1=CC2=C(C[C@H]([C@H](O2)C3=CC(=C(C(=C3)OC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C4=CC(=C(C(=C4)OC(=O)C)OC(=O)C)OC(=O)C)C(=C1)OC(=O)C |
| Reference | [1]. Wang CC, et al. Prodrug of green tea epigallocatechin-3-gallate (Pro-EGCG) as a potent anti-angiogenesis agent for endometriosis in mice. Angiogenesis. 2013 Jan;16(1):59-69.<br>[2]. KalaiselviIgnasimuthu, et al. Enhanced bioaccessibility of green tea polyphenols and lipophilic activity of EGCG octaacetate on gram-negative bacteria. Volume 105, May 2019, Pages 103-109. |
