EGFR/ErbB-2/ErbB-4 inhibitor-3

• CAT Number: I010597
• CAS Number: 881001-19-0
• Molecular Formula: C17H11ClFN5O
• Molecular Weight: 355.75
• Purity: ≥95%
• Synonyms: N-[4-(3-chloro-4-fluoroanilino)pyrido[3,4-d]pyrimidin-6-yl]but-2-ynamide
• InChI: InChI=1S/C17H11ClFN5O/c1-2-3-16(25)24-15-7-11-14(8-20-15)21-9-22-17(11)23-10-4-5-13(19)12(18)6-10/h4-9H,1H3,(H,20,24,25)(H,21,22,23)
• InChIKey: DLPSDPPZXRJQOY-UHFFFAOYSA-N
• SMILES: CC#CC(=O)NC1=NC=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl

EGFR/ErbB-2/ErbB-4 inhibitor-3（Cat No.:I010597）is a small molecule designed to inhibit the activity of multiple members of the ErbB family of receptor tyrosine kinases, including EGFR (Epidermal Growth Factor Receptor), ErbB-2 (HER2), and ErbB-4. These receptors are involved in cell signaling pathways that regulate cell growth, survival, and differentiation, and are often overexpressed or mutated in various cancers. By blocking these receptors, this inhibitor aims to disrupt cancer cell proliferation and survival, offering potential therapeutic benefits in treating cancers such as breast, lung, and gastric cancers. Further research is ongoing to assess its efficacy.