Eglumegad hydrochloride

• CAT Number: I040820
• Molecular Formula: C8H12ClNO4
• Molecular Weight: 221.64
• Purity: ≥95%
• Synonyms: (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid;hydrochloride
• InChI: InChI=1S/C8H11NO4.ClH/c9-8(7(12)13)2-1-3-4(5(3)8)6(10)11;/h3-5H,1-2,9H2,(H,10,11)(H,12,13);1H/t3-,4-,5-,8-;/m0./s1
• InChIKey: XZLCJPCFWPIGEU-PLFKSMQJSA-N
• SMILES: C1CC(C2C1C2C(=O)O)(C(=O)O)N.Cl

Eglumegad hydrochloride(CAT: I040820) is a potent, selective antagonist of group II metabotropic glutamate receptors (mGluR2 and mGluR3). It is widely used in neuroscience research to investigate glutamatergic signaling and its role in various central nervous system disorders, including anxiety, depression, schizophrenia, and neurodegeneration. By modulating glutamate transmission, Eglumegad hydrochloride aids in elucidating the function of mGluRs in synaptic plasticity, neuroprotection, and neurotransmitter release. This compound offers high specificity and reliable performance in both in vitro and in vivo studies. Its utility in probing mGluR-mediated pathways makes it a valuable tool in the development of novel therapeutics targeting neurological and psychiatric conditions.