For research use only. Not for therapeutic Use.
EHMT2-IN-1 is a potent EHMT inhibitor, with IC50s of all <100 nM for EHMT1 peptide, EHMT2 peptide and cellular EHMT2. Used in the research of blood disorder or cancer[1].
EHMT2-IN-1 (Compound 108) potent EHMT inhibitor, with IC50s of all <100 nM for EHMT1 peptide, EHMT2 peptide and cellular EHMT2[1].
| Catalog Number | I046215 |
| CAS Number | 2230849-55-3 |
| Synonyms | 2-N-[4-methoxy-3-[4-(methylaminomethyl)pyrazol-1-yl]phenyl]-4-N,6-dimethylpyrimidine-2,4-diamine |
| Molecular Formula | C18H23N7O |
| Purity | ≥95% |
| InChI | InChI=1S/C18H23N7O/c1-12-7-17(20-3)24-18(22-12)23-14-5-6-16(26-4)15(8-14)25-11-13(9-19-2)10-21-25/h5-8,10-11,19H,9H2,1-4H3,(H2,20,22,23,24) |
| InChIKey | DJSJHTKOFPOYRZ-UHFFFAOYSA-N |
| SMILES | CC1=CC(=NC(=N1)NC2=CC(=C(C=C2)OC)N3C=C(C=N3)CNC)NC |
| Reference | [1]. John Emmerson Campbell, et al. Amine-substituted heterocyclic compounds as ehmt2 inhibitors and methods of use thereof. WO2018118842A1 |
