For research use only. Not for therapeutic Use.
EHMT2-IN-2 is a potent EHMT inhibitor, with IC50s of all <100 nM for EHMT1 peptide, EHMT2 peptide and cellular EHMT2. Used in the research of blood disease or cancer[1].
EHMT2-IN-2 (Compound 200) is a potent EHMT inhibitor, with IC50s of all < 100 nM for EEHMT1 peptide, EHMT2 peptide and cellular EHMT2[1].
| Catalog Number | I019238 |
| CAS Number | 2230850-47-0 |
| Synonyms | 2-N-[4-methoxy-3-(3-methyl-1H-pyrrolo[2,3-c]pyridin-2-yl)phenyl]-4-N,6-dimethylpyrimidine-2,4-diamine |
| Molecular Formula | C21H22N6O |
| Purity | ≥95% |
| InChI | InChI=1S/C21H22N6O/c1-12-9-19(22-3)27-21(24-12)25-14-5-6-18(28-4)16(10-14)20-13(2)15-7-8-23-11-17(15)26-20/h5-11,26H,1-4H3,(H2,22,24,25,27) |
| InChIKey | AZRYONWATLLNFX-UHFFFAOYSA-N |
| SMILES | CC1=CC(=NC(=N1)NC2=CC(=C(C=C2)OC)C3=C(C4=C(N3)C=NC=C4)C)NC |
| Reference | [1]. John Emmerson Campbell, et al. Amine-substituted heterocyclic compounds as ehmt2 inhibitors and methods of use thereof. WO2018118842A1. |
